ASK YOUR DOCTOR,
“When’s the right time to take NUZYRA each day?”
Your antibiotic treatment may have started in the hospital
Once you get home, take your NUZYRA tablets once daily as prescribed by your doctor
Getting back to YOU AGAIN NUZYRA may be the treatment option you’ve been looking for
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Your treatment path starts here
Your doctor chose once-daily* NUZYRA to treat certain bacterial infections.
*For community-acquired pneumonia, take 2 NUZYRA 300-mg tablets twice on Day 1.
In Clinical Studies
See how NUZYRA helps
Treatment duration is 7-14 days.
| Acute skin infections | Community-acquired pneumonia | |
|---|---|---|
|
Early improvements (After first dose) |
2-3 Days |
3-5 Days |
|
Treated successfully (After last dose) |
7-14 Days |
5-10 Days |
In clinical studies, patients were treated for 7 to 14 days. Doctors assessed how patients responded to NUZYRA at two key time points. An early assessment measured whether symptoms began improving shortly after treatment started. A later assessment evaluated whether the infection was successfully treated after therapy was completed.
Side effects of NUZYRA
Most common side effects include:
Nausea, vomiting, increased liver function tests, elevated blood pressure (hypertension), headache, diarrhea, difficulty sleeping (insomnia), and constipation
- Nausea and vomiting are more common on Days 1 and 2 in people who receive the initial oral doses
- Reactions at the infusion site (pain, swelling, redness, and irritation) were also common in people who received NUZYRA as an infusion
- These are not all of the possible side effects of NUZYRA
- Tell your healthcare provider about any side effect that bothers you or that does not go away
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How to take NUZYRA
When taking NUZYRA tablets, it’s important to:
Fast for at least 4 hours
and then take with water only
Not eat or drink
(except water) for 2 hours after taking
NUZYRA
Not consume dairy products, antacids, or multivitamins
for 4
hours after taking NUZYRA
NUZYRA can be taken at bedtime or upon waking
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DOSING SCHEDULE
Your dosage of NUZYRA is specific to your condition
Treatment duration is 7-14 days
Acute skin infections
Initial Dose
Days 1-2
450 mg (3 tablets together) once a day
Maintenance Dose
300 mg (2 tablets) once daily
Tablets are not shown at actual size.
Community-acquired pneumonia
Initial Dose
TWICE on Day 1*:
300 mg (2 tablets)
Maintenance Dose
300 mg (2 tablets) once daily
Tablets are not shown at actual size.
*For community-acquired pneumonia, take 2 NUZYRA 300-mg tablets twice on Day 1.
Dosing Reminders
Take NUZYRA exactly as prescribed
- The initial doses are important for NUZYRA to work properly
- NUZYRA may not work properly if you break the fasting window
-
Skipping doses or not finishing all of the medication prescribed may:
- Make the treatment not work as well
- Increase the likelihood that bacteria will develop resistance and will not be treatable by NUZYRA or other antibacterial drugs in the future
Missed a dose? Find help in FAQs
HOSPITAL DOSING
Did you start antibiotic treatment for your infection at a hospital?
Steps to get NUZYRA
Get NUZYRA delivered to your home
Your doctor will send your NUZYRA prescription to a specialty pharmacy
This may not be your usual pharmacy, so be sure to get the specialty pharmacy’s information from the doctor
Answer the call from the specialty pharmacy
It’s important to speak with the pharmacy promptly to confirm details. If they leave a voicemail, please call back
After you speak to the pharmacy, they’ll ship NUZYRA directly to your home
The majority of people will receive NUZYRA within 24 hours of the prescription being sent to the pharmacy
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Coverage and Affordability
NUZYRA is covered by most insurers, including:
- Commercial insurance
- Basic Medicare
- Medicare Advantage/Supplemental
- Low-income subsidy
- Medicaid
- Tricare
Insurance coverage and reimbursement for NUZYRA are not guaranteed. Coverage and reimbursement depend on your insurance plan. It’s recommended you contact your insurance provider to verify NUZYRA coverage and reimbursement. Certain factors like personal insurance and/or deductibles may impact the price of your prescription.
Eligible patients may
Pay as little as
With the NUZYRA Copay Program, the majority of eligible patients with commercial insurance may pay as little as $0. Patients must be commercially insured. May not be used if the patient is enrolled in a government-funded prescription insurance program.†
NEED ASSISTANCE?
Support for caregivers
How you and your caregiver can help
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The specialty pharmacy will call them
Once the doctor has prescribed NUZYRA, expect a call from the specialty pharmacy. They will ship NUZYRA directly to the patient’s home
Partner to stay on track
Help them set up a daily routine to take NUZYRA and manage the fasting requirements
Monitor for side effects
Notify the doctor’s office immediately if you notice any side effects (e.g., nausea, vomiting, diarrhea)
Frequently asked questions
Treatment & Experience
How do I know NUZYRA is working?
In clinical studies, most patients began seeing symptom improvement at:
- 2-3 days for people with acute skin infections
- 3-5 days for people with community-acquired pneumonia
Although it is common to start feeling better early in the course of therapy, take NUZYRA exactly as directed. Skipping doses or not completing the full course of therapy may:
- decrease the effectiveness of the immediate treatment
- increase the likelihood that bacteria will develop resistance and will not be treatable by NUZYRA or other antibiotics in the future
How long until I feel better?
The treatment duration of NUZYRA ranges from 7-14 days. Take NUZYRA for as long as your doctor has prescribed.
What if I miss a dose?
Contact your doctor’s office immediately for further instructions. It’s important that you take NUZYRA exactly as prescribed.
What if the pharmacy hasn’t called?
Please call the specialty pharmacy directly. Contact your doctor’s office to find out which specialty pharmacy your prescription was sent to for fulfillment. They should be able to give you the contact information for the specialty pharmacy.
Morning vs night dosing?
It depends. NUZYRA must be taken with water only, which may be more convenient to do first thing in the morning or just before bedtime. As a reminder, here are the fasting rules for NUZYRA:
- 4 hours before taking: No food or drink
- For 2 hours after taking: No food or drink (except water)
- For 4 hours after taking: Avoid dairy, antacids, and multivitamins
Talk to your doctor about which time to take your medicine.
What can I do as a caregiver?
You can help the person taking NUZYRA by reminding them to take their medication at the same time daily, encourage them to finish their prescription as prescribed, and support them through the fasting window. Look out for any side effects–especially nausea, vomiting, or diarrhea in the first couple days–and contact the doctor’s office to report any issues.
Safety & Medication
Who should not take NUZYRA?
Do not take NUZYRA if you are allergic to tetracycline-class drugs. Ask your doctor or pharmacist for a list of these medicines if you are not sure.
Can I take it for a cold or flu?
Some infections are caused by viruses and not by bacteria. Examples include viral infections such as the common cold or flu. Antibacterial medicines, including NUZYRA, do not treat viral infections. NUZYRA should only be used to treat bacterial infections. Call your healthcare provider if you think your condition is not getting better while you are taking NUZYRA.
Can I take it while pregnant or breastfeeding?
Tell your doctor about all of your medical conditions, including if you are pregnant or plan to become pregnant, as NUZYRA may harm an unborn baby.
Taking NUZYRA during tooth development (during the last half of pregnancy, infancy, and during childhood up to the age of 8 years) may cause serious side effects including permanent discoloration of teeth and slow bone growth of your baby. Talk to your doctor before taking NUZYRA if you plan to become pregnant, or if you are already taking NUZYRA and plan to become pregnant.
Breastfeeding during treatment with NUZYRA and for 4 days after the last dose is not recommended.
Tell your doctor if you are breastfeeding or plan to breastfeed. NUZYRA passes into your milk and may harm your baby. You and your doctor should decide if you will take NUZYRA or breastfeed. You should not do both.
Can I take it with other medications or supplements?
Tell your doctor about all the medicines you take, including prescription drugs (such as oral contraceptives) and over-the-counter medicines, vitamins, and herbal supplements. NUZYRA and certain other medicines may affect each other or may cause side effects. It is especially important to mention if you are taking any of the following:
- blood thinners (anticoagulants) such as warfarin
- antacids that contain aluminum, calcium, or magnesium or iron-containing products.
What if I have diarrhea?
Clostridioides difficile-associated diarrhea (CDAD) is an infection of your intestines (bowels) that can happen with many antibacterial medicines like NUZYRA and may cause mild diarrhea to life-threatening swelling of your intestines (colitis). Call your healthcare provider right away if you get stomach cramps, fever, watery diarrhea, diarrhea that does not go away, or bloody stools.
Will I have side effects?
The most common side effects of NUZYRA include: nausea, vomiting, increased liver function tests, elevated blood pressure (hypertension), headache, diarrhea, difficulty sleeping (insomnia), and constipation.
- Nausea and vomiting are more common on Day 1 and 2 in people who receive the initial oral doses
- Reactions at the infusion site (pain, swelling, redness, and irritation) were also common in people who received NUZYRA as an infusion
- These are not all of the possible side effects of NUZYRA
- Tell your healthcare provider about any side effect that bothers you or that does not go away